April 2025
galapagos
Sole Financial Adviser
Sale of immunology and oncology programmes to Onco3R Therapeutics

Galapagos

Van Lanschot Kempen acted as Sole Financial Adviser to Galapagos in the sale of a portfolio of oncology and immunology programmes to Onco3R Therapeutics

Transaction highlights

  • Galapagos has sold a portfolio of small molecule programmes in oncology and immunology to Onco3R Therapeutics in exchange for Onco3R equity and future milestone-based considerations 
  • The programmes involve a Phase 1-ready SIK3 inhibitor for immunology indications, as well as a precision oncology portfolio featuring small molecule candidates targeting among others FGFR3, SMARCA2, and P53 Y220C 
  • The sale to Onco3R highlights Galapagos’ strategic transformation, following its January 2025 announcement to discontinue its small molecule discovery programmes and seek potential partners, in order to focus on long-term value creation in cell therapy 
  • This transactions further builds on Van Lanschot Kempen's decade-long relationship with Galapagos, which began with leading Galapagos’ Euronext IPO in May 2005 and continued through several follow-on and M&A transactions, including the divestment of Jyseleca to Alfasigma in 2024

Company description

Galapagos is a global biotechnology company with operations in Europe, the Unites States and Asia, dedicated to transforming patient outcomes through life-changing science and innovation. The company focuses on areas of high unmet medical need, combining compelling science, technology, and collaborative approaches to build a robust pipeline of best-in-class medicines in oncology and immunology, including a decentralised T-cell manufacturing network.

Background Van Lanschot Kempen Life Sciences & Healthcare

In the last twelve months, Van Lanschot Kempen has successfully completed a large number of transactions in its Life Sciences & Healthcare franchise. Recent transactions include:

  • Co-Manager in the USD 748 million capital increase by Abivax
  • Joint Bookrunner in the USD 201 million capital increase by Pharvaris 
  • Financial Adviser in Maat Pharma’s €36 million venture debt facility from the European Investment Bank
  • Lead Manager in the USD 345 million capital increase by Merus
  • Co-Placement Agent in DBV Technologies’ up to USD 307 million financing
  • Placement Agent in MaaT Pharma’s €13 million capital increase
  • Sole Financial Adviser in Pharming’s SEK 725 million public takeover of Abliva
  • Sole Financial Adviser in GENFIT’s royalty financing up to €85 million
  • Sole Financial Adviser in IO Biotech’s c. €58 million loan facility from the European Investment Bank
  • Financial Adviser in the USD 479 million US Public Offering by NewAmsterdam Pharma
  • Sole Financial Adviser to SNIPR Biome in securing a €20 million venture debt facility from the European Investment Bank

Jan de Kerpel Van Lanschot Kempen

Jan De Kerpel

Managing Director
Life Sciences & Healthcare

Emailj.dekerpel@vanlanschotkempen.com