July 2025
pharvaris
Joint Bookrunner
USD 201 million
US Public Offering

Pharvaris

Van Lanschot Kempen acted as Joint Bookrunner in the USD 201 million capital increase by Pharvaris

Transaction highlights

  • Pharvaris, a late-stage biotechnology company focused on developing oral treatments for hereditary angioedema successfully raised USD 201 million in equity financing
  • Capital increase of 8,250,000 new ordinary shares and 1,312,500 additional new ordinary shares (related to the full exercise of the underwriters’ option) at a price of USD 20.00 per share alongside pre-funded warrants to purchase 500,000 ordinary shares at a price of USD 19.99 per pre-funded warrant, generating gross proceeds of USD 201 million for Pharvaris at a discount of 13.5% to the pre-launch closing price
  • The transaction was launched on the back of positive momentum in the HAE space and Pharvaris’ announcement expecting to pull the topline read-out of its RAPIDe-3 study six months forward to Q4 2025
  • Pharvaris intends to use the net proceeds of this offering primarily to fund its late stage clinical programs and commercialisation-related expenses
  • Van Lanschot Kempen acted as Joint Bookrunner and the only European Bank in a US-dominated banking syndicate and is proud to have continuously supported Pharvaris after being involved in its 2021 US IPO

Company description

Pharvaris is a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to potentially address all types of bradykinin-mediated angioedema. Pharvaris intends to provide injectable-like efficacy™ and placebo-like tolerability with the convenience of oral therapies to prevent and treat bradykinin-mediated angioedema attacks. With positive data in both Phase 2 prophylaxis and on-demand studies in HAE, Pharvaris is currently evaluating the efficacy and safety of deucrictibant in a pivotal Phase 3 study for the prevention of HAE attacks (CHAPTER-3) and a pivotal Phase 3 study for the on-demand treatment of HAE attacks (RAPIDe-3).

Background Van Lanschot Kempen Life Sciences & Healthcare

In the last twelve months, Van Lanschot Kempen has successfully completed a large number of transactions in its Life Sciences & Healthcare franchise. Recent transactions include:

  • Lead Manager in the USD 345 million capital increase by Merus
  • Co-Placement Agent in DBV Technologies’ up to USD 307 million financing
  • Placement Agent in MaaT Pharma’s €13 million capital increase
  • Sole Financial Adviser in Pharming’s SEK 725 million public takeover of Abliva
  • Sole Financial Adviser in GENFIT’s royalty financing up to €185 million
  • Sole Financial Adviser in IO Biotech’s c. €58 million loan facility from the European Investment Bank
  • Financial Adviser in the USD 479 million US Public Offering by NewAmsterdam Pharma
  • Sole Financial Adviser to SNIPR Biome in securing a €20 million venture debt facility from the European Investment Bank
 

Jan de Kerpel Van Lanschot Kempen

Jan De Kerpel

Managing Director
Life Sciences & Healthcare

Emailj.dekerpel@vanlanschotkempen.com
Kathrin Erfurth Van Lanschot Kempen

Kathrin Erfurth

Managing Director
Equity Capital Markets
Robin van Wijk Van Lanschot Kempen

Robin van Wijk

Executive Director
Equity Capital Markets