July 2025
pharvaris
Joint Bookrunner
USD 201 million
US Public Offering

Pharvaris

Van Lanschot Kempen acted as Joint Bookrunner in the USD 201 million capital increase by Pharvaris

Transaction highlights

  • Pharvaris, a late-stage biotechnology company focused on developing oral treatments for hereditary angioedema successfully raised USD 201 million in equity financing
  • Capital increase of 8,250,000 new ordinary shares and 1,312,500 additional new ordinary shares (related to the full exercise of the underwriters’ option) at a price of USD 20.00 per share alongside pre-funded warrants to purchase 500,000 ordinary shares at a price of USD 19.99 per pre-funded warrant, generating gross proceeds of USD 201 million for Pharvaris at a discount of 13.5% to the pre-launch closing price
  • The transaction was launched on the back of positive momentum in the HAE space and Pharvaris’ announcement expecting to pull the topline read-out of its RAPIDe-3 study six months forward to Q4 2025
  • Pharvaris intends to use the net proceeds of this offering primarily to fund its late stage clinical programs and commercialisation-related expenses
  • Van Lanschot Kempen acted as Joint Bookrunner and the only European Bank in a US-dominated banking syndicate and is proud to have continuously supported Pharvaris after being involved in its 2021 US IPO

Company description

Pharvaris is a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to potentially address all types of bradykinin-mediated angioedema. Pharvaris intends to provide injectable-like efficacy™ and placebo-like tolerability with the convenience of oral therapies to prevent and treat bradykinin-mediated angioedema attacks. With positive data in both Phase 2 prophylaxis and on-demand studies in HAE, Pharvaris is currently evaluating the efficacy and safety of deucrictibant in a pivotal Phase 3 study for the prevention of HAE attacks (CHAPTER-3) and a pivotal Phase 3 study for the on-demand treatment of HAE attacks (RAPIDe-3).

Background Van Lanschot Kempen Life Sciences & Healthcare

In the last twelve months, Van Lanschot Kempen has successfully completed a large number of transactions in its Life Sciences & Healthcare franchise. Recent transactions include:

  • Lead Manager in the USD 345 million capital increase by Merus
  • Co-Placement Agent in DBV Technologies’ up to USD 307 million financing
  • Placement Agent in MaaT Pharma’s €13 million capital increase
  • Sole Financial Adviser in Pharming’s SEK 725 million public takeover of Abliva
  • Sole Financial Adviser in GENFIT’s royalty financing up to €185 million
  • Sole Financial Adviser in IO Biotech’s c. €58 million loan facility from the European Investment Bank
  • Financial Adviser in the USD 479 million US Public Offering by NewAmsterdam Pharma
  • Sole Financial Adviser to SNIPR Biome in securing a €20 million venture debt facility from the European Investment Bank
 

Contact

Jan de Kerpel Van Lanschot Kempen

Jan De Kerpel

Managing Director
Life Sciences & Healthcare

EmailMail Jan De Kerpel
Kathrin Erfurth Van Lanschot Kempen

Kathrin Erfurth

Managing Director
Equity Capital Markets
Robin van Wijk Van Lanschot Kempen

Robin van Wijk

Executive Director
Equity Capital Markets