uniCure

Van Lanschot Kempen acted as Joint Bookrunner in the upsized USD 345 million capital increase by uniQure

Transaction highlights

uniQure, a commercial-stage biotechnology company focused on developing gene therapies for severe diseases, successfully raised USD 300 million in equity financing, which was increased to USD 345 million following the exercise in full of the underwriters’ 15% overallotment option
The transaction was priced at a price of USD 47.50 per share, representing no discount vis-à-vis the pre-launch closing price on Wednesday 24 September
The transaction was launched on the back of topline three-year Phase I/II data for its lead asset, AMT-130—an AAV gene therapy for Huntington’s disease and the first potential disease-modifying treatment for this condition. A Biologics License Application (BLA) submission is anticipated in the first quarter of 2026, with a potential commercial launch later that year
Van Lanschot Kempen played an instrumental role in securing orders from new tier-1 long-only and international life science investors
uniQure intends to use the net proceeds from this offering to fund its AMT-130 program through BLA submission and potential launch, advance other pipeline assets, pursue business development initiatives and research projects, and support general corporate purposes
Van Lanschot Kempen acted as Joint Bookrunner and was the only European bank in a US-dominated banking syndicate, and is proud to support uniQure for the first time in a successful equity raise

uniQure is dedicated to transforming the lives of patients with severe genetic diseases through innovative gene therapies
Their leadership in the field of genomic medicine is demonstrated by the regulatory approval of Hemgenix®, the first gene therapy for haemophilia B, which has been outlicensed to CSL
The company has developed a broad pipeline of gene therapies, with programs at multiple stages of development, focusing on Huntington’s disease, refractory temporal lobe epilepsy, ALS, Fabry disease, and other severe diseases
uniQure is headquartered in Amsterdam, the Netherlands, with a US office in Lexington, Massachusetts, and is listed on the Nasdaq in the US (QURE)

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